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Coffee-Related Heart Attacks and Genes

Genes determine coffee-related heart attack risk,

A genetic mutation that slows the rate that the body metabolizes caffeine increases individuals' risk of having a heart attack if they drink much coffee, investigators report in the Journal of the American Medical Association.

[. . .] The team's results showed that only carriers of the gene mutation for slow caffeine metabolism were at increased risk of heart attack associated with drinking coffee.

For these patients, the increased risk was 64 percent for four or more cups per day over the previous year compared with patients who drank less than one cup per day.

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